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Dihydropyridines do not alter sinus node discharge rateor atrioventricular conduction. The absence of mastcells protects the brain and spinal cord from the potentiallydisruptive effects of the edema ofallergic reactions.
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The high rate of adverse drug events in children receiving prolongedoutpatient parenteral antibiotic therapy for osteomyelitis. The morecommon cultural and biologic variations encountered in theclinical setting are described in this chapter.